We are always looking for talented students, research assistants and postdoctoral researchers. Please send your CV and brief introduction of your background, future plan and research interest to “kpwulab@gmail.com”. You will be further contacted for scheduling interview.
For those who are not currently living in Taiwan, applying TIGP-CBMB program and enroll as a PhD student is the easiest way to join us.
The positions are open and ready to begin at any time.
Who you are:
- TIGP-CBMB graduate students, NTU-IBS graduate students are always welcome to contact me for personal meet and discussions.
- Owning a Master degree or a PhD degree in life sciences or biochemistry-related trainings.
- Familiar with NMR or X-ray crystallography or biophysics instrument
- Having basic idea of molecular biology and protein expression.
- Knowing mammalian cell culture is a plus.
- Knowing Linux and/or programming is a plus.
The research goal:
- Regulating protein ubiquitination and ultimately provide chance to cure human diseases.
- Understanding the mechanism of protein oligomerization, fibrilization or misfolding related to diseases or key physiological enzymes.
THE research tools:
- Structural biology: solution NMR, X-ray crystallography, cryo-EM
- Biophysics: Isothermal calorimetry, Octet biosensor, Fluorescence polarization, real-time fluorescence detection and all available biophysical instrument in IBC and Academia Sinica.
- Computational biology: large-scale data process and molecular simulation dynamics
- Biochemical assays, enzyme kinetics, and cellular responses.
Ongoing projects:
- Ubiquitination and protein degradation in cancer signaling pathway by E3 ligase.
- Ubiquitination and protein degradation in autoimmune response and anti-viral defense by ISG15 and interferon gamma.
- Design of small proteins or chemical compounds targeting ubiquitination enzymes.
- Mechanism of amyloid fibril formation.
KPWu's group research site 